LSBio
IHC-plus™ GIPR / GIP Receptor Antibody (N-Terminus)

Anti-GIPR / GIP Receptor antibody IHC of human Adrenal, Pheochromocytoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GIPR / GIP Receptor Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all GIPR / GIP Receptor antibodies →
$403.00each
Catalog Number: LS-A3840-50

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Overview

Description
GIP Receptor antibody LS-A3840 is an unconjugated rabbit polyclonal antibody to human GIP Receptor (GIPR) (N-Terminus). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
IHC, IHC-P
Reactivity
Hu
Predicted Reactivity
Bovine, Dog
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
GIP receptor | GIPR | PGQTL2 | GIP-R
Recommended Dilution: IHC-P
15 - 20 µg/ml
UniProt Number
P48546
NCBI GenBank
NM_000164 | NP_000155.1
SwissProt
P48546

Target

Target
GIPR / GIP Receptor
Antigen Species
Human
Specificity
Human GIPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GHRHR (100%), ZNF839 (61%).
Epitope
Human GIPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZNF839 (61%).
Gene Name
GIPR

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 18 amino acid peptide from N-Terminus extracellular domain of human GIPR. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Panda, Bovine, Dog (94%); Marmoset, Horse (89%); Hamster, Rabbit (83%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Regulation of aldosterone secretion by several aberrant receptors including for glucose-dependent insulinotropic peptide in a patient with an aldosteronoma. Lampron A, Bourdeau I, Oble S, Godbout A, Schrch W, Arjane P, Hamet P, Lacroix A. The Journal of clinical endocrinology and metabolism. 2009;94:750-6.

PubMed: 19066304

Coexistence of Myelolipoma and Primary Bilateral Macronodular Adrenal Hyperplasia With GIP-Dependent Cushing's Syndrome. Larose S, Bondaz L, Mermejo LM, Latour M, Prosmanne O, Bourdeau I, Lacroix A. Frontiers in endocrinology. 2019 September;10.

PubMed: 31572300 · PMC: PMC6749096

A case of ACTH-independent macronodular adrenal hyperplasia associated with multiple endocrine neoplasia type 1. Masanori Yoshida, Maiko Hiroi, Tsuneo Imai, Toyone Kikumori, Tatsuhito Himeno, Yasuhiro Nakamura, Hironobu Sasano, Masanobu Yamada, Yoshiko Murakami, Sigeo Nakamura, Yutaka Oiso. Endocrine Journal. 2011 March;58:269-77.

PubMed: 21415556

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