Anti-GC / VDBP antibody IHC of human blood plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ GC / Vitamin D-Binding Protein Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

See all GC / Vitamin D-Binding Protein antibodies â†’

$383.00each

Catalog Number: LS-B4807-0.25

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Overview

Description: Vitamin D-Binding Protein antibody LS-B4807 is an unconjugated rabbit polyclonal antibody to human Vitamin D-Binding Protein (GC). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
Application: ELISA, IHC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: GC | Gc-globulin | HDBP | Group-specific component | GRD3 | VDB | VDBG | VDBP | Vitamin D-binding protein
Recommended Dilution: IHC-P: 5 µg/ml
UniProt Number: P02774
NCBI GenBank: NM_000583 | NP_000574.2
SwissProt: P02774

Target

Target: GC / Vitamin D-Binding Protein
Antigen Species: Human
Specificity: Recognizes Vitamin D binding protein (VDBP), the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scavenging system. VDBP is a 52-58 kD plasma protein synthesized mainly by hepatocytes. Polymorphisms in the gene give rise to three major electrophoretic variants, Gc1, Gc1s and Gc1f that differ by amino acid substitutions as well as glycosylations. The physiological significance of these phenotypes has yet to be determined.
Epitope: Recognizes Vitamin D binding protein (VDBP), the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scavenging system. VDBP is a 52-58 kD plasma protein synthesized mainly by hepatocytes. Polymorphisms in the gene give rise to three major electrophoretic variants, Gc1, Gc1s and Gc1f that differ by amino acid substitutions as well as glycosylations. The physiological significance of these phenotypes has yet to be determined.
Gene Name: GC

Antibody

Host Species: Rabbit
Clonality: Polyclonal
Origin Species: Human

Immunogen

Immunogen: Native human vitamin D binding protein

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: PBS, 0.09% Sodium Azide
Concentration: 5 mg/mL
Volume: 0.25 Milliliter
Animal Free: No
Carrier-Free: Yes
Preservative: Yes
Purification Method: Protein G Affinity

Storage & Handling

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS