LSBio
IHC-plus™ FZD6 / Frizzled 6 Antibody (N-Terminus)

Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

IHC-plus™ FZD6 / Frizzled 6 Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all FZD6 / Frizzled 6 antibodies →
$403.00each
Catalog Number: LS-A4481-50

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Overview

Description
Frizzled 6 antibody LS-A4481 is an unconjugated rabbit polyclonal antibody to human Frizzled 6 (FZD6) (N-Terminus). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
IHC
Reactivity
Hu
Predicted Reactivity
Bovine, Horse, Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Frizzled family receptor 6 | FZ-6 | HFZ6 | Frizzled 6 | Frizzled-6 | FZD6 | Frizzled homolog 6 | FZ6 | NDNC10
Recommended Dilution: IHC-P
14 µg/ml
UniProt Number
O60353
SwissProt
O60353

Target

Target
FZD6 / Frizzled 6
Antigen Species
Human
Specificity
Human Frizzled-6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTMR10 (47%).
Epitope
Human Frizzled-6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTMR10 (47%).
Gene Name
FZD6

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 17 amino acid peptide from N-Terminus extracellular domain of human Frizzled-6. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Horse (94%); Elephant, Pig, Opossum (88%); Panda, Bat, Rabbit (82%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. Bengochea A, de Souza MM, Lefranois L, Le Roux E, Galy O, Chemin I, Kim M, Wands JR, Trepo C, Hainaut P, Scoazec JY, Vitvitski L, Merle P. British journal of cancer. 2008;99:143-50.

PubMed: 18577996 · PMC: PMC2453022


Gene Deconvolution Reveals Aberrant Liver Regeneration and Immune Cell Infiltration in Alcohol-Associated Hepatitis. Adam Kim, Xiaoqin Wu, Daniela S Allende, Laura E Nagy. Hepatology (Baltimore, Md.). 2021 August;74:987-1002.

PubMed: 33619773 · PMC: PMC8475730

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