Anti-FMR1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

IHC-plus™ FMR1 / FMRP Antibody (aa594-607)

Primary AntibodyLSBio Guarantee

Antibody:	Goat Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:	Hamster, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rabbit, Rat
Format:	Liquid

$495.00each

Catalog Number: LS-B3953-50

Unit Size

Quantity

For bulk orders or custom formulations:

Overview

Description: FMRP antibody LS-B3953 is an unconjugated goat polyclonal antibody to FMRP (FMR1) (aa594-607) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application: ELISA, IHC, IHC-P, WB
Reactivity: Ham, Hu, Mml, Ms, NHP, Por, Rb, Rt
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: FMR1 | FMRP | POF | Protein FMR-1 | Premature ovarian failure 1 | Fragile X mental retardation 1 | FRAXA | POF1
Recommended Dilution: IHC-P: 2.5 µg/ml
Recommended Dilution: WB: 0.1 - 0.3 µg/ml
UniProt Number: Q06787
NCBI GenBank: NM_002024 | NP_002015.1
SwissProt: Q06787

Target

Target: FMR1 / FMRP
Antigen Species: Human
Specificity: Human FMR1.
Epitope: Human FMR1.
Gene Name: FMR1

Antibody

Host Species: Goat
Clonality: Polyclonal
Origin Species: Human

Immunogen

Immunogen: Peptide with sequence C-RTGKDRNQKKEKPD, from the internal region (near the C-Terminus) of the protein sequence according to NP_002015.1.
Immunogen Type: Peptide

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration: 0.5 mg/mL
Animal Free: No
Carrier-Free: No
Preservative: Yes
Purification Method: Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer: TBS

Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/ß-catenin, and mTOR signaling during corticogenesis. Cristine R Casingal, Takako Kikkawa, Hitoshi Inada , Yukio Sasaki, Noriko Osumi. Molecular brain. 2020 Dec;13:167. PubMed: 33323119 PMC: PMC7739466

Submit a Publication