FKBP38 / FKBP8 Antibody
Catalog Number: LS-C401688
4 sizes / from $260.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Immunohistochemistry of paraffin-embedded human tonsil tissue using FKBP8 Antibody at dilution of 1:100
IHC-plus™ FKBP38 / FKBP8 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B15749-50
Catalog Number: LS-B15749
For bulk orders or custom formulations:
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- Description
- FKBP8 antibody LS-B15749 is an unconjugated rabbit polyclonal antibody to FKBP8 (FKBP38) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- 38 kDa FKBP | 38 kDa FK506-binding protein | FKBP-8 | FK506-binding protein 8 | FKBP38 | FKBP8 | HFKBP38 | FKBP-38 | Rotamase | FK506 binding protein 8, 38kDa | FK506-binding protein 8 (38kD) | FKBPr38 | PPIase FKBP8
- Recommended Dilution: IHC-P
- 10 µg/ml
- Recommended Dilution: WB
- 1:500 - 1:5000
- UniProt Number
- Q14318
- NCBI GenBank
- NM_012181 | NP_036313.3
- SwissProt
- Q14318
Target
- Target
- FKBP38 / FKBP8
- Antigen Species
- Human
- Specificity
- Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
- Epitope
- Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
- Gene Name
- FKBP8
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
