LSBio
IHC-plus™ FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M2F12)

Anti-FGFR1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M2F12)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$567.00each
Catalog Number: LS-B6232-50

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Overview

Description
FGF Receptor 1 antibody LS-B6232 is an unconjugated mouse monoclonal antibody to FGF Receptor 1 (FGFR1) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC, IHC-F, IHC-P, IP, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
BFGF receptor | BFGF-R | BFGF-R-1 | CD331 | Cek1 | CD331 antigen | FGFR1 | FGFR1/PLAG1 fusion | FLT2 | Fgf-flg | FGFBR | FGFR-1 | Fms-like tyrosine kinase 2 | HBGFR | HH2 | Hydroxyaryl-protein kinase | FGF receptor 1 | Fms-related tyrosine kinase 2 | Proto-oncogene c-Fgr | BFGFR | CEK | FLT-2 | HBGF receptor | KAL2 | OGD
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
1 µg/ml
UniProt Number
P11362
NCBI GenBank
CAA47375.1 | NM_023110
SwissProt
P11362

Target

Target
FGFR1 / FGF Receptor 1
Antigen Species
Human
Specificity
Reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1a. Reacts with human, rat, and mouse receptor. Other species untested.
Epitope
Reacts with the NH2-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu30 and ala74 of FGFr1a. Reacts with human, rat, and mouse receptor. Other species untested.
Gene Name
FGFR1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
M2F12
Origin Species
Human

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C to -70°C for up to 1 year. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice. Hao Wang, Chirag A Shah, Liping Hu, Weiqi Huang, Leonidas C Platanias, Elizabeth A Eklund. The Journal of biological chemistry. 2020 July;295:9663-9675. PubMed: 32467231 PMC: PMC7363149
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