Anti-CXCR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ CXCR4 Antibody (clone 12G5)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin
Reactivity:	Cynomolgus Monkey, Human, Non-Human Primate, Rhesus Macaque
Format:	Liquid

$470.00each

Catalog Number: LS-B1986-50

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Overview

Description: CXCR4 antibody LS-B1986 is an unconjugated mouse monoclonal antibody to CXCR4 from human. It is reactive with human, african green monkey, baboon and other species. Validated for Flow, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application: FC, IF, IHC, IHC-F, IHC-P
Reactivity: Cyno, Hu, NHP, Rhes
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD184 | CD184 antigen | Cmkar4 | Cxc chemokine receptor 4 | CXCR-4 | CXCR4 | CXC-R4 | D2S201E | FB22 | Fusin | HM89 | LCR1 | NPY3R | NPYRL | NPYY3R | Npyy3 | HSY3RR | SDF-1 receptor | WHIM | C-x-c chemokine receptor 4 | LESTR | Neuropeptide Y receptor Y3 | NPYR
Recommended Dilution: IHC-P: 10 µg/ml
UniProt Number: P61073
NCBI GenBank: NM_003467 | NP_003458.1
SwissProt: P61073

Target

Target: CXCR4
Antigen Species: Human
Gene Name: CXCR4

Antibody

Host Species: Mouse
Clonality: Monoclonal
Clone: 12G5
Light Chain: Kappa Light Chain
Origin Species: Human

Immunogen

Immunogen: CP-MAC-infected Sup-T1 cells

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: PBS, pH 7.2, 0.09% Sodium Azide
Concentration: 0.5 mg/mL
Animal Free: No
Carrier-Free: Yes
Preservative: Yes
Purification Method: Affinity Purified

Storage & Handling

Storage Conditions: Store undiluted at 4°C. Avoid freezing.
Recommended Storage Buffer: PBS

Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L, Wu MX. The Journal of biological chemistry. 2007;282:9547-55.

PubMed: 17289675 · PMC: PMC2366813

Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Isnardi I, Ng YS, Menard L, Meyers G, Saadoun D, Srdanovic I, Samuels J, Berman J, Buckner JH, Cunningham-Rundles C, Meffre E. Blood. 2010;115:5026-36.

PubMed: 20231422 · PMC: PMC3373152

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