CUL2 / Cullin 2 Antibody
Catalog Number: LS-C405513
4 sizes / from $260.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human, Mouse
Format: Liquid
Anti-CUL4A / Cullin 4A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
IHC-plus™ Cullin 4A / CUL4A Antibody (aa1-25)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$505.00each
Catalog Number: LS-B360-50
Catalog Number: LS-B360
For bulk orders or custom formulations:
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- Description
- CUL4A antibody LS-B360 is an unconjugated rabbit polyclonal antibody to human CUL4A (Cullin 4A) (aa1-25). Validated for ELISA, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
- Application
- ELISA, IHC, IHC-P, IP, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CUL-4A | CUL4A | Cullin-4A | Cullin 4A
- Recommended Dilution: ELISA
- 1:2000 - 1:10000
- Recommended Dilution: IHC-P
- 1:500
- Recommended Dilution: IP
- 1:500
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- Q13619
- NCBI GenBank
- NM_003589 | NP_003580.1
- SwissProt
- Q13619
Target
- Target
- Cullin 4A / CUL4A
- Antigen Species
- Human
- Specificity
- Reacts with human Cullin 4A. Cross reactivity is expected against mouse Cul4A based on a high degree of sequence homology. Cross reactivity with other human cullins may occur.
- Epitope
- Reacts with human Cullin 4A. Cross reactivity is expected against mouse Cul4A based on a high degree of sequence homology. Cross reactivity with other human cullins may occur.
- Gene Name
- CUL4A
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-Terminal region near amino acids 1-25 of Human Cul4A coupled to KLH.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Antiserum, 0.01% Sodium Azide
- Concentration
- 85 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at 4°C or -20°C. Avoid freeze-thaw cycles.
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM. Cell. 1996;85:829-39.
PubMed: 8681378
Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Higa LA, Mihaylov IS, Banks DP, Zheng J, Zhang H. Nature cell biology. 2003;5:1008-15.
PubMed: 14578910
Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma. Mayura Meerang, Jessica Kreienbühl, Vanessa Orlowski, Seraina L C Müller, Michaela B Kirschner, Isabelle Opitz. Cancers. 2020 November;12.
PubMed: 33233664 · PMC: PMC7699720
