LSBio
IHC-plus™ CUL1 / Cullin 1 Antibody (aa750-776)

Anti-CUL1 / Cullin 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.

IHC-plus™ CUL1 / Cullin 1 Antibody (aa750-776)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
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$526.00each
Catalog Number: LS-B357-50

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Overview

Description
Cullin 1 antibody LS-B357 is an unconjugated rabbit polyclonal antibody to human Cullin 1 (CUL1) (aa750-776). Validated for ELISA, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CUL1 | Cullin 1 | Cullin-1 | CUL-1
Recommended Dilution: ELISA
1:2000 - 1:10000
Recommended Dilution: IHC-P
1:500
Recommended Dilution: WB
1:500 - 1:1000
UniProt Number
Q13616
SwissProt
Q13616

Target

Target
CUL1 / Cullin 1
Antigen Species
Human
Specificity
Reacts with human Cullin 1. Cross reactivity is expected against mouse Cul1 based on sequence homology.
Epitope
Reacts with human Cullin 1. Cross reactivity is expected against mouse Cul1 based on sequence homology.
Gene Name
CUL1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-Terminal near amino acids 750-776 of Human Cul1 coupled to KLH.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Antiserum, 0.01% Sodium Azide
Concentration
85 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Unpurified (Serum / Ascites / Supernatant)

Storage & Handling

Storage Conditions
Store at 4°C or -20°C. Avoid freeze-thaw cycles.

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM. Cell. 1996;85:829-39.

PubMed: 8681378


ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Ohta T, Michel JJ, Schottelius AJ, Xiong Y. Molecular cell. 1999;3:535-41.

PubMed: 10230407

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