LSBio
IHC-plus™ Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2)

Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ Complement C6 Antibody (C-Terminus, clone 056B-214.2.4.2)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
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$526.00each
Catalog Number: LS-B3294-0.05

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Overview

Description
Complement C6 antibody LS-B3294 is an unconjugated mouse monoclonal antibody to human Complement C6 (C-Terminus). Validated for ELISA, Flow and IHC. Tested on 20 paraffin-embedded human tissues.
Application
ELISA, FC, IHC, IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
C6 | Complement component C6 | Complement C6 | Complement component 6
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P13671
SwissProt
P13671

Target

Target
Complement C6
Antigen Species
Human
Specificity
Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
Epitope
Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
Gene Name
C6

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
056B-214.2.4.2
Origin Species
Human

Immunogen

Immunogen
Purified human C6

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
BBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
bbs

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