CLDN8 / Claudin 8 Antibody
Catalog Number: LS-C402327
4 sizes / from $260.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Anti-CLDN8 / Claudin 8 antibody IHC of rat colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
IHC-plus™ CLDN8 / Claudin 8 Antibody (C-Terminus)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Dog, Mouse, Rat |
| Format: | Liquid |
$495.00each
Catalog Number: LS-B5505-50
Catalog Number: LS-B5505
For bulk orders or custom formulations:
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- Description
- Claudin 8 antibody LS-B5505 is an unconjugated rabbit polyclonal antibody to Claudin 8 (CLDN8) (C-Terminus) from rat. It is reactive with mouse, rat and dog. Validated for IF, IHC and WB. Cited in 1 publication.
- Application
- IF, IHC, IHC-F, IHC-P, WB
- Reactivity
- Can, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Claudin 8 | Claudin-8 | CLDN8
- Recommended Dilution: IF/ICC
- 2.7 µg/ml
- Recommended Dilution: IHC-P
- 10 µg/ml
- Recommended Dilution: WB
- 1 - 3 µg/ml
- UniProt Number
- P56748
- NCBI GenBank
- NM_199328
- SwissProt
- P56748
Target
- Target
- CLDN8 / Claudin 8
- Antigen Species
- Rat
- Specificity
- Reacts with mouse, rat, and dog Claudin-8. On Western blots, it identifies the target band at ~30kD. Reactivity has been confirmed with TCMK-1 mouse kidney, KNRK rat kidney, and MDCK dog kidney cell lysates by Western blotting, and with ethanol-fixed, frozen mouse colon tissue by immunohistochemistry / immunofluorescence.
- Epitope
- Reacts with mouse, rat, and dog Claudin-8. On Western blots, it identifies the target band at ~30kD. Reactivity has been confirmed with TCMK-1 mouse kidney, KNRK rat kidney, and MDCK dog kidney cell lysates by Western blotting, and with ethanol-fixed, frozen mouse colon tissue by immunohistochemistry / immunofluorescence.
- Gene Name
- CLDN8
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide derived from the C-Terminus of mouse and rat Claudin-8.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.09% Sodium Azide
- Concentration
- 0.25 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
- Recommended Storage Buffer
- PBS
Glucocorticoids Regulate Tight Junction Permeability of Lung Epithelia by Modulating Claudin 8. Kielgast F, Schmidt H, Braubach P, Winkelmann VE, Thompson KE, Frick M, Dietl P, Wittekindt OH. American journal of respiratory cell and molecular biology. 2016;54:707-17. PubMed: 26473470
