LSBio
IHC-plus™ CES2 / Esterase Antibody (clone 4F12)

Anti-CES2 / Esterase antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ CES2 / Esterase Antibody (clone 4F12)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$383.00each
Catalog Number: LS-B6190-50

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Overview

Description
Esterase antibody LS-B6190 is an unconjugated mouse monoclonal antibody to human Esterase (CES2). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
RUO
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Carboxylesterase 2 | CES2 | CE-2 | CES2A1 | Cocaine esterase | Esterase | ICE | HCE-2 | PCE-2
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1:500 - 1:1000
UniProt Number
O00748
NCBI GenBank
NM_003869, NP_003860.2
SwissProt
O00748

Target

Target
CES2 / Esterase
Antigen Species
Hu
Specificity
Human CES2
Epitope
Human CES2
Gene Name
CES2

Antibody

Host Species
Ms
Clonality
Monoclonal
Clone
4F12
Light Chain
κ
Origin Species
Hu

Immunogen

Immunogen
CES2 (NP_003860, 514 aa ~ 622 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
0.41 mg/mL
Animal Free
No
Carrier-Free
Yes
Purification Method
Prot A

Storage & Handling

Storage Conditions
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR. Verbrugge SE, Al M, Assaraf YG, Kammerer S, Chandrupatla DM, Honeywell R, Musters RP, Giovannetti E, O'Toole T, Scheffer GL, Krige D, de Gruijl TD, Niessen HW, Lems WF, Kramer PA, Scheper RJ, Cloos J, Ossenkoppele GJ, Peters GJ, Jansen G. Oncotarget. 2016;7:5240-57. PubMed: 26496029 PMC: PMC4868683
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