LSBio
IHC-plus™ CDK5 Antibody (C-Terminus)

Anti-CDK5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.

IHC-plus™ CDK5 Antibody (C-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$526.00each
Catalog Number: LS-B353-50

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Overview

Description
CDK5 antibody LS-B353 is an unconjugated rabbit polyclonal antibody to CDK5 (C-Terminus) from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, IP, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CDK5 | CDKN5 | Cell division protein kinase 5 | Crk6 | Cyclin-dependent kinase 5 | Protein kinase CDK5 splicing | PSSALRE | TPKII catalytic subunit
Recommended Dilution: ELISA
1:5000 - 1:20000
Recommended Dilution: IHC-P
1:500
Recommended Dilution: IP
1:100
Recommended Dilution: WB
1:500 - 1:5000
UniProt Number
Q00535
SwissProt
Q00535

Target

Target
CDK5
Antigen Species
Human
Specificity
Antiserum will specifically react with a 35 kDa cdk5 (p31) protein from human, rat and mouse tissue. No reaction was observed against other related cyclin dependent kinases. Cross reactivity with cdk5 (p31) from other species may also occur.
Epitope
Antiserum will specifically react with a 35 kDa cdk5 (p31) protein from human, rat and mouse tissue. No reaction was observed against other related cyclin dependent kinases. Cross reactivity with cdk5 (p31) from other species may also occur.
Gene Name
CDK5

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
CDK5 (p31) peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Antiserum, 0.01% Sodium Azide
Concentration
85 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Unpurified (Serum / Ascites / Supernatant)

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation. Qiaoyun Chu, Liyong Wang, Jie Zhang, Wei Wang, Youxin Wang. Cancer medicine. 2021 Jun;;10:3689-3699. PubMed: 33960694 PMC: PMC8178504

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