Anti-CD6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ CD6 Antibody (clone MEM-98)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:	Human
Format:	Liquid

$383.00each

Catalog Number: LS-B7296-50

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Overview

Description: CD6 antibody LS-B7296 is an unconjugated mouse monoclonal antibody to human CD6. Validated for Flow, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Application: FC, IHC, IHC-P, IP, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD6 molecule | T12 | TP120 | CD6 | CD6 antigen
Recommended Dilution: FC: 1:1
Recommended Dilution: IHC-P: 10 µg/ml
UniProt Number: P30203
NCBI GenBank: NM_006725 | NP_006716.3
SwissProt: P30203

Target

Target: CD6
Antigen Species: Human
Specificity: Recognizes the human CD6 cell surface antigen, a 120kD glycoprotein expressed by mature T lymphocytes
Epitope: Recognizes human CD6, also known as T12 or TP120. CD6 is a ~100-130 kD type 1 single pass trans-membrane protein member of the immunoglobulin superfamily. CD6 possesses 3 scavenger receptor cysteine rich domains in it's extracellular sequence. The membrane proximal SRCR3 contains the epitope responsible for interaction with CD166, also known as Activated Leukocyte Cell Adhesion Molecule or CD166. Multiple gene transcripts have been detected encoding CD6 in man resulting in the production of a number of CD6 isoforms. Recognizes an external epitope located in the membrane-distal SRCR domain 1 and is expected to recognize all CD6 isoforms so far identified,. CD6 has been implicated as a therapeutic target for a number of autoimmune conditions including Sjogren's syndrome, rheumatoid arthritis and psoriasis.
Gene Name: CD6

Antibody

Host Species: Mouse
Clonality: Monoclonal
Clone: MEM-98
Origin Species: Human

Immunogen

Immunogen: Purified CD6 antigen.

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: PBS, 0.09% Sodium Azide
Concentration: 1 mg/mL
Animal Free: No
Carrier-Free: Yes
Preservative: Yes
Purification Method: Protein G Affinity

Storage & Handling

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS