LSBio
IHC-plus™ CD30 Antibody (clone rCD30/412)

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ CD30 Antibody (clone rCD30/412)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Recombinant Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B16227-50

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Overview

Description
CD30 antibody LS-B16227 is an unconjugated mouse recombinant monoclonal antibody to human CD30. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Application
IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD30L receptor | CD30 | Cytokine receptor CD30 | D1S166E | Ki-1 | Ki-1 antigen | TNFRSF8 | CD30 antigen
Recommended Dilution: IHC-P
1:50
UniProt Number
P28908
NCBI GenBank
NM_001243 | NP_001234.3
SwissProt
P28908

Target

Target
CD30
Antigen Species
Human
Specificity
Recognizes a single chain glycoprotein of 105/120 kDa , identified as CD30/Ki-1. CD30 is synthesized as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Epitope
Recognizes a single chain glycoprotein of 105/120 kDa , identified as CD30/Ki-1. CD30 is synthesized as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Gene Name
TNFRSF8

Antibody

Host Species
Mouse
Clonality
Recombinant Monoclonal
Clone
rCD30/412
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human TNFRSF8 protein. Antigen Molecular Weight: 105-120 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.