LSBio
IHC-plus™ CCT2 / CCT Beta Antibody

Anti-CCT2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ CCT2 / CCT Beta Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all CCT2 / CCT Beta antibodies →
$470.00each
Catalog Number: LS-B4861-50

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Overview

Description
CCT Beta antibody LS-B4861 is an unconjugated rabbit polyclonal antibody to human CCT Beta (CCT2). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
99D8.1 | CCT-beta | CCTB | CCT2 | PRO1633 | TCP-1-beta | TCP1 Beta
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
1:500 - 1:3000
UniProt Number
P78371
SwissProt
P78371

Target

Target
CCT2 / CCT Beta
Antigen Species
Human
Specificity
Human TCP1 beta. Predicted cross-reactivity based on amino acid sequence homology: mouse (97%), rat (97%), rabbit (100%), bovine (98%), pig (100%), zebrafish (87%).
Epitope
Human TCP1 beta. Predicted cross-reactivity based on amino acid sequence homology: mouse (97%), rat (97%), rabbit (100%), bovine (98%), pig (100%), zebrafish (87%).
Gene Name
CCT2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Recombinant protein encompassing a sequence within the center region of human TCP1 beta. The exact sequence is proprietary.
Immunogen Type
Proprietary / Undisclosed

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
0.1 M Tris, pH 7, 0.1 M Glycine, 10% Glycerol, 0.01% Thimerosal
Concentration
1 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
0.1 M Tris

Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer. Carr AC, Khaled AS, Bassiouni R, Flores O, Nierenberg D, Bhatti H, Vishnubhotla P, Manuel JP, Santra S, Khaled AR. Oncotarget. 2017;8:110273-110288.

PubMed: 29299146


Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. Anne E Showalter , Ana C Martini , Daniel Nierenberg, Kristen Hosang, Naima Ahmed Fahmi, Priya Gopalan, Amr S Khaled, Wei Zhang, Annette R Khaled. Scientific reports. 2020 Jan;10:798.

PubMed: 31964905 · PMC: PMC6972895

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