LSBio
IHC-plus™ CASP1 / Caspase 1 Antibody (aa371-390, clone 14F468)

Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.

IHC-plus™ CASP1 / Caspase 1 Antibody (aa371-390, clone 14F468)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$383.00each
Catalog Number: LS-B112-50

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Overview

Description
Caspase 1 antibody LS-B112 is an unconjugated mouse monoclonal antibody to Caspase 1 (CASP1) (aa371-390) from human. It is reactive with human and mouse. Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Application
ICC, IHC, IHC-P, WB
Reactivity
Hu, Ms
Predicted Reactivity
Rat
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Caspase-1 | CASP-1 | CASP1 | CASP1 nirs variant 1 | Caspase 1 | ICE | ICE-like protease | IL-1 beta-converting enzyme | IL-1BC | IL1BC | IL1BCE | p45 | IL1B-convertase | Interleukin-1 beta convertase
Recommended Dilution: IHC-P
20 µg/ml
Recommended Dilution: WB
0.5 - 2 µg/ml
UniProt Number
P29466
SwissProt
P29466

Target

Target
CASP1 / Caspase 1
Antigen Species
Human
Specificity
A synthetic peptide corresponding to amino acids 371-390 RKVRFSFEQPDGRAQMPTTE of human caspase-1 was used as immunogen. It will cross-react with mouse and rat Caspase-1, based on NCBI BLAST.
Epitope
will recognize full-length Caspase-1 and cleaved caspase-1 forms that retain amino acids 371-390 of the Caspase-1 protein.
Gene Name
CASP1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
14F468
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
Two synthetic peptides from the human caspase-1 protein (aa 371-390 and aa 31-45)
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.