LSBio
IHC-plus™ APEX1 / APE1 Antibody

Anti-APEX1 / APE1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:250.

IHC-plus™ APEX1 / APE1 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$495.00each
Catalog Number: LS-B3179-50

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Overview

Description
APE1 antibody LS-B3179 is an unconjugated rabbit polyclonal antibody to human APE1 (APEX1). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC, IHC-F, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AP endonuclease class I | AP lyase | APE | APE-1 | APEN | APEX1 | APE1 | APEX nuclease | Redox factor-1 | AP endonuclease 1 | APEX | APX | Protein REF-1 | REF-1 | REF1
Recommended Dilution: IHC-P
1:250
Recommended Dilution: WB
1:500
UniProt Number
P27695
SwissProt
P27695

Target

Target
APEX1 / APE1
Antigen Species
Human
Specificity
Specific to the human APE/ref-1protein. Competitively inhibited from recognizing the APE/ref-1 antigen in tissues using APE/ref-1 protein. Inhibits repair activity of ape protein.
Epitope
Specific to the human APE/ref-1protein. Competitively inhibited from recognizing the APE/ref-1 antigen in tissues using APE/ref-1 protein. Inhibits repair activity of ape protein.
Gene Name
APEX1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Affinity purified human Apurinic/Apyrimidinic Endonuclease (APE/ref-1) fusion protein.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.2, 0.05% Sodium Azide, 40% Glycerol
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Decisive role of apurinic/apyrimidinic endonuclease/Ref-1 in initiation of cell death. Cho KJ, Kim HJ, Park SC, Kim HW, Kim GW. Molecular and cellular neurosciences. 2010 Nov;45:267-76. PubMed: 20637286

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