ACKR3 / CXCR7 Antibody
Catalog Number: LS-C664889-100
100 µg / $338.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunoprecipitation, Western Blot
Reactivity: Human
Format: Liquid
Anti-CXCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
IHC-plus™ ACKR3 / CXCR7 Antibody (aa100-150)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Bovine, Dog, Hamster, Horse, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rabbit, Rat |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B1815-50
Catalog Number: LS-B1815
For bulk orders or custom formulations:
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- Description
- CXCR7 antibody LS-B1815 is an unconjugated rabbit polyclonal antibody to CXCR7 (ACKR3) (aa100-150) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
- Application
- FC, IHC, IHC-P, WB
- Reactivity
- Bov, Can, Ham, Hr, Hu, Mml, Ms, NHP, Por, Rb, Rt
- Predicted Reactivity
- Xenopus
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Chemokine orphan receptor 1 | CMKOR1 | CXCR7 | CXC-R7 | GPRN1 | RDC1 | RDC-1 | CXCR-7 | G-protein coupled receptor 159 | GPR159
- Recommended Dilution: FC
- 1 - 10 µg/ml
- Recommended Dilution: IHC-P
- 10 µg/ml
- Recommended Dilution: WB
- 4 - 6 µg/ml
- UniProt Number
- P25106
- NCBI GenBank
- NM_020311 | NP_064707.1
- SwissProt
- P25106
Target
- Target
- ACKR3 / CXCR7
- Antigen Species
- Human
- Specificity
- A portion of amino acids 100-150 of human RDC1
- Epitope
- A portion of amino acids 100-150 of human RDC1.
- Gene Name
- ACKR3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- A synthetic peptide (QHNQWPMGELTC) corresponding amino acids 106-117 of human CXCR7/RDC1 was used as the immunogen, GenBank NP_064707.1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Dog, Horse, Rabbit, Pig, Opossum (100%); Platypus, Xenopus (92%); Turkey (83%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Tris-Glycine, 0.05% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- Tris-Glycine
Heteromerization of chemokine (C-X-C motif) receptor 4 with alpha 1A/B-adrenergic receptors controls alpha 1-adrenergic receptor function. Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, Volkman BF, Gaponenko V, Majetschak M. Proceedings of the National Academy of Sciences of the United States of America. Mar.
PubMed: 25775528
New Insights into Mechanisms and Functions of Chemokine (C-X-C Motif) Receptor 4 Heteromerization in Vascular Smooth Muscle. Evans AE, Tripathi A, LaPorte HM, Brueggemann LI, Singh AK, Albee LJ, Byron KL, Tarasova NI, Volkman BF, Cho TY, Gaponenko V, Majetschak M. International journal of molecular sciences. 2016;17.
PubMed: 27331810 · PMC: PMC4926503
Commercially available antibodies directed against a-adrenergic receptor subtypes and other G protein-coupled receptors with acceptable selectivity in flow cytometry experiments. Abhishek Tripathi, Vadim Gaponenko, Matthias Majetschak. Naunyn-Schmiedeberg's archives of pharmacology. 2016 Feb;389:243-8.
PubMed: 26660071 · PMC: PMC4718873
