LSBio
IHC-plus™ ACKR3 / CXCR7 Antibody (aa100-150)

Anti-CXCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ ACKR3 / CXCR7 Antibody (aa100-150)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Dog, Hamster, Horse, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rabbit, Rat
Format:Liquid
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$383.00each
Catalog Number: LS-B1815-50

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Overview

Description
CXCR7 antibody LS-B1815 is an unconjugated rabbit polyclonal antibody to CXCR7 (ACKR3) (aa100-150) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
FC, IHC, IHC-P, WB
Reactivity
Bov, Can, Ham, Hr, Hu, Mml, Ms, NHP, Por, Rb, Rt
Predicted Reactivity
Xen
Intended Use
RUO
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Chemokine orphan receptor 1 | CMKOR1 | CXCR7 | CXC-R7 | GPRN1 | RDC1 | RDC-1 | CXCR-7 | G-protein coupled receptor 159 | GPR159
Recommended Dilution: FC
1 - 10 µg/ml
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
4 - 6 µg/ml
UniProt Number
P25106
SwissProt
P25106

Target

Target
ACKR3 / CXCR7
Antigen Species
Hu
Specificity
A portion of amino acids 100-150 of human RDC1
Epitope
A portion of amino acids 100-150 of human RDC1.
Gene Name
ACKR3

Antibody

Host Species
Rb
Clonality
Polyclonal
Isotype
IgG
Origin Species
Hu

Immunogen

Immunogen
A synthetic peptide (QHNQWPMGELTC) corresponding amino acids 106-117 of human CXCR7/RDC1 was used as the immunogen, GenBank NP_064707.1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Dog, Horse, Rabbit, Pig, Opossum (100%); Platypus, Xenopus (92%); Turkey (83%).

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
Tris-Glycine, 0.05% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
Tris-Glycine
Heteromerization of chemokine (C-X-C motif) receptor 4 with alpha 1A/B-adrenergic receptors controls alpha 1-adrenergic receptor function. Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, Volkman BF, Gaponenko V, Majetschak M. Proceedings of the National Academy of Sciences of the United States of America. Mar. PubMed: 25775528

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