LSBio
IGF1 Antibody

IGF1 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Neutralization, Western Blot
Reactivity:Human, Mouse, Rat
Format:Lyophilized
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$849.00each
Catalog Number: LS-C7504-200

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Overview

Description
IGF1 antibody LS-C7504 is an unconjugated mouse monoclonal antibody to IGF1 from human. It is reactive with human, mouse and rat. Validated for IHC, IP, Neut and WB. Cited in 1 publication.
Application
IHC, IHC-P, IP, Neut, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
IGF-IA | IGF-IB | IGFI | IBP1 | IGF-I | IGF1 | Insulin-like growth factor 1 | Insulin-like growth factor I | Insulin-like growth factor IA | Insulin-like growth factor IB | Mechano growth factor | Somatomedin-C | IGF1A | MGF
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: Other
Neutralization: 10 - 20 µg/ml
Recommended Dilution: WB
0.5 - 2 µg/ml
UniProt Number
P05019
SwissProt
P05019

Target

Target
Human IGF1
Antigen Species
Human
Epitope
Recognizes human IGF1. Cross-reactivity with IGF-II: ~40%. Species cross-reactivity: mouse, rat and possibly chicken. Occasional difficulty neutralizing rat IGF1 due to binding protein interference.
Gene Name
IGF1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Light Chain
Kappa Light Chain

Immunogen

Immunogen
Human insulin-like growth factor I (IGF1) purified from human plasma.
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Supplied as a lyophilized powder from 0.1M Tris-glycine, pH 7.4, 0.15mM sodium chloride, 0.1mM EDTA. No preservative added.
Preservative
No
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
0.1M Tris-glycine|0.15mM sodium chloride
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance. Somasundaram R, Zhang G, Fukunaga-Kalabis M, Perego M, Krepler C, Xu X, Wagner C, Hristova D, Zhang J, Tian T, Wei Z, Liu Q, Garg K, Griss J, Hards R, Maurer M, Hafner C, Mayerhöfer M, Karanikas G, Jalili A, Bauer-Pohl V, Weihsengruber F, Rappersberger K, Koller J, Lang R, Hudgens C, Chen G, Tetzlaff M, Wu L, Frederick DT, Scolyer RA, Long GV, Damle M, Ellingsworth C, Grinman L, Choi H, Gavin BJ, Dunagin M, Raj A, Scholler N, Gross L, Beqiri M, Bennett K, Watson I, Schaider H, et al. Nature communications. 2017;8:607. PubMed: 28928360

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