Immunofluorescent analysis of MCF-7 cells using IER3 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
IER3 / IEX-1 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C499092-50
Catalog Number: LS-C499092
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- Description
- IEX-1 antibody LS-C499092 is an unconjugated rabbit polyclonal antibody to human IEX-1 (IER3). Validated for ELISA and IF.
- Application
- ELISA, IF, IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- DIF-2 | DIF2 | Gly96, mouse, homolog of | IEX1 | IEX-1L | Immediate early protein GLY96 | Immediate early response 3 | Immediately early gene X-1 | GLY96 | IER3 | IEX-1 | Protein DIF-2 | Protein PRG1 | PRG1 | Anti-death protein
- UniProt Number
- P46695
- NCBI GenBank
- NM_003897 | NP_003888.2
- SwissProt
- P46695
Target
- Target
- Human IER3 / IEX-1
- Antigen Species
- Human
- Epitope
- May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
- Gene Name
- IER3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS