HSPA8 / HSC70 Antibody (FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C500063-50
Catalog Number: LS-C500063
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- Description
- HSC70 antibody LS-C500063 is an FITC-conjugated rabbit polyclonal antibody to human HSC70 (HSPA8). Validated for ELISA.
- Application
- ELISA
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Heat shock 70 kDa protein 8 | Heat shock 70kd protein 10 | Heat shock 70kD protein 8 | Heat shock cognate protein 54 | HSP71 | HSPA10 | HSC71 | HSP73 | HSPA8 | LPS-associated protein 1 | Heat shock 70kDa protein 8 | NIP71 | HSC54 | HSC70 | LAP1
- UniProt Number
- P11142
- NCBI GenBank
- NM_006597 | NP_006588.1
- SwissProt
- P11142
Target
- Target
- Human HSPA8 / HSC70
- Antigen Species
- Human
- Epitope
- Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP.
- Gene Name
- HSPA8
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Heat shock cognate 71 kDa protein protein (418-597AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS