HPV11 E7 Antibody (clone 3D6F1)
Catalog Number: LS-C758546-100
100 µL / $529.00
Antibody: Mouse Monoclonal
Applications: Western Blot
Reactivity: Human, Virus / Viral Antigen
Format: Liquid
HPV16 E7 Antibody (clone 716-D1)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Virus / Viral Antigen |
| Format: | Liquid |
$438.00each
Catalog Number: LS-C58368-0.2
Catalog Number: LS-C58368
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- HPV16 E7 antibody LS-C58368 is an unconjugated mouse monoclonal antibody to virus HPV16 E7. Validated for ELISA and WB.
- Application
- ELISA, IHC, WB
- Reactivity
- Vir
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- UniProt Number
- P03129
- NCBI GenBank
- NP_041326.1
- SwissProt
- P03129
Target
- Target
- Virus HPV16 E7
- Antigen Species
- Virus / Viral Antigen
- Epitope
- Recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Reacts with both the monomer and dimer forms of the E7 protein of HPV-18.
- Gene Name
- E7
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 716-D1
- Isotype
- IgG2a
Immunogen
- Immunogen
- Oncoprotein E7 from human papillomavirus 16.
- Immunogen Type
- Virus / Viral Particle
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, less than 0.1% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
