HLA-DR1 Antibody (clone MEM-267, Concentrated)

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Antibody:	Mouse Monoclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Western Blot
Reactivity:	Human
Format:	Liquid

$481.00each

Catalog Number: LS-C204185-0.1

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Description: HLA-DR1 antibody LS-C204185 is an unconjugated mouse monoclonal antibody to human HLA-DR1. Validated for ELISA, Flow and WB.
Application: ELISA, FC, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies

Target: Human HLA-DR1
Antigen Species: Human
Epitope: HLA-DR1 belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kD. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. The antibody MEM-267 specifically binds to the empty but not peptide-loaded form of HLADR1.

Immunogen: Purified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies.
Immunogen Type: Native Protein (Purified from Natural Source)