GZMB / Granzyme B Antibody (clone GRB-7)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot
Reactivity:	Human
Format:	Liquid

$878.00each

Catalog Number: LS-C121911-250

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Description: Granzyme B antibody LS-C121911 is an unconjugated mouse monoclonal antibody to human Granzyme B (GZMB). Validated for IHC and WB.
Application: IHC, IHC-F, IHC-P, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | GZMB | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
Recommended Dilution: WB: 1:20
UniProt Number: P10144
NCBI GenBank: NM_004131|NP_004122.2
SwissProt: P10144

Target: Human GZMB / Granzyme B
Antigen Species: Human
Epitope: Recognizes the 33kD human serine protease granzyme B. Does not react with human granzyme A. It is used as a marker for NK-cells and activated cytotoxic T-cells (CTL). This protease is localized in cytoplasmic granules and gives a granular staining pattern. Granzyme B is involved in target cell apoptosis during lymphocyte mediated cyto-toxicity. Exocytosis of granzyme containing granules in the cytoplasm of the target cell will lead to induction of DNA fragmentation and apoptosis of the target cell.
Gene Name: GZMB

Storage Conditions: Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.

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