WB of GZMA / Granzyme A antibody. Lane 1: JURKAT Cell Lysate. Lane 2: CEM Cell Lysate. Lane 3: RAJI Cell Lysate.
GZMA / Granzyme A Antibody (aa175-190)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Lyophilized |
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- Description
- Granzyme A antibody LS-C312742 is an unconjugated rabbit polyclonal antibody to human Granzyme A (GZMA) (aa175-190). Validated for IHC and WB. Cited in 5 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CTLA3 | CTL tryptase | Granzyme-1 | H factor | HF | HFSP | Granzyme A | GZMA | Fragmentin-1 | Hanukah factor | Hanukkah factor
- UniProt Number
- P12544
- NCBI GenBank
- NM_006144 | NP_006135.1
- SwissProt
- P12544
Target
- Target
- Human GZMA / Granzyme A
- Antigen Species
- Human
- Gene Name
- GZMA
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human Granzyme A(175-190 aa DRKVCNDRNHYNFNPV).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- NaCl
Lesional CD4+ IFN-?+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis. Maehara T, Mattoo H, Ohta M, Mahajan VS, Moriyama M, Yamauchi M, Drijvers J, Nakamura S, Stone JH, Pillai SS. Annals of the rheumatic diseases. 2017 February;76:377-385.
PubMed: 27358392 · PMC: PMC5435236
Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis. Takashi Maehara, Naoki Kaneko, Cory A Perugino, Hamid Mattoo, Jesper Kers, Hugues Allard-Chamard, Vinay S Mahajan, Hang Liu, Samuel Jh Murphy, Musie Ghebremichael, David Fox, Aimee S Payne, Robert Lafyatis, John H Stone, Dinesh Khanna, Shiv Pillai. The Journal of clinical investigation. 2020 May;130:2451-2464.
PubMed: 31990684 · PMC: PMC7190971
CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease. Cory A Perugino, Naoki Kaneko, Takashi Maehara, Hamid Mattoo, Jesper Kers, Hugues Allard-Chamard, Vinay S Mahajan, Hang Liu, Emanuel Della-Torre, Samuel J H Murphy, Musie Ghebremichael, Zachary S Wallace, Marcy B Bolster, Liam M Harvey, Geetha Mylvaganam, Yesim Tuncay, Lloyd Liang, Sydney B Montesi, Xiuwei Zhang, Akira Tinju, Keita Mochizuki, Ryusuke Munemura, Mizuki Sakamoto, Masafumi Moriyama, Seiji Nakamura, Nir Yosef, John H Stone, Shiv Pillai. The Journal of allergy and clinical immunology. 2021 January;147:368-382.
PubMed: 32485263 · PMC: PMC7704943
CD4+CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum. Hugues Allard-Chamard, Faisal Alsufyani, Naoki Kaneko, Kelly Xing, Cory Perugino, Vinay S Mahajan, Joseph L Wheat, George S Deepe Jr, James Loyd, Shiv Pillai. Journal of immunology (Baltimore, Md. : 1950). 2021 February;206:524-530.
PubMed: 33328214 · PMC: PMC7978153
Cytotoxic CD8sup>+/sup> T cells may be drivers of tissue destruction in Sjögren's syndrome. Naoki Kaneko, Hu Chen, Cory A Perugino, Takashi Maehara, Ryusuke Munemura, Shiho Yokomizo, Junsei Sameshima, Thomas J Diefenbach, Katherine R Premo, Akira Chinju, Yuka Miyahara, Mizuki Sakamoto, Masafumi Moriyama, John H Stone, Seiji Nakamura, Shiv Pillai. Scientific reports. 2022 September;12:15427.
PubMed: 36104369 · PMC: PMC9475031