GRN antibody (1 ug/ml) staining of A431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
GRN / Granulin Antibody (aa248-259)
Primary AntibodyLSBio Guarantee
| Antibody: | Goat Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Hamster, Human, Mouse, Non-Human Primate, Rat |
| Format: | Liquid |
$514.00each
Catalog Number: LS-C154960-100
Catalog Number: LS-C154960
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- Description
- Granulin antibody LS-C154960 is an unconjugated goat polyclonal antibody to Granulin (GRN) (aa248-259) from human. It is reactive with human, mouse, rat and other species. Validated for Peptide-ELISA and WB. Cited in 1 publication.
- Application
- ELISA, IHC, WB
- Reactivity
- Ham, Hu, Ms, NHP, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Acrogranin | CLN11 | Epithelin precursor | GEP | GRN | gp88 | Granulin | Granulin-epithelin | Granulins | PC cell-derived growth factor | PCDGF | PEPI | PGRN | Proepithelin | Progranulin
- UniProt Number
- P28799
- NCBI GenBank
- NM_002087 | NP_002078.1
- SwissProt
- P28799
Target
- Target
- Human GRN / Granulin
- Antigen Species
- Human
- Epitope
- Human GRN / Granulin. This antibody is expected to recognize the C-Terminal part of Granulin-3.
- Gene Name
- GRN
Antibody
- Host Species
- Goat
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Peptide with sequence PQDTVCDLIQSK, from the internal of the protein sequence according to NP_002078.1.
- Immunogen Type
- Peptide
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
- Concentration
- 0.5 mg/mL
- Preservative
- Yes
- Purification Method
- Ammonium Sulfate Precipitation
Storage & Handling
- Storage Conditions
- Aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- TBS
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations. Holler CJ, Taylor G, Deng Q, Kukar T. eNeuro. 2017 August;4. PubMed: 28828399 PMC: PMC5562298