LSBio
Gr-1 Antigen Antibody (clone RB6-8C5, RPE)

Gr-1 Antigen Antibody (clone RB6-8C5, RPE)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Flow Cytometry
Reactivity:Mouse
Format:Lyophilized
See all Mouse Gr-1 Antigen antibodies →
$413.00each
Catalog Number: LS-C44780-100

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Overview

Description
Gr-1 Antigen antibody LS-C44780 is an RPE-conjugated rat monoclonal antibody to mouse Gr-1 Antigen. Validated for Flow.
Application
FC
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: FC
1:1 - 1:5

Target

Target
Mouse Gr-1 Antigen
Antigen Species
Mouse
Epitope
Recognizes the mouse Gr-1 antigen, a 21-25kD cell surface protein that belongs to the Ly-6 family of proteins. Clone Reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated. The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported. Clone RB6-8C5 has been reported to deplete mouse mature neutrophils in vivo. XXX recommend the use of MCA2387EL for functional studies.

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
RB6-8C5
Isotype
IgG2b

Immunogen

Immunogen
Normal murine bone marrow cells
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Phycoerythrin
Format
Lyophilized
Formulation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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