Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
FOLR1 / Folate Receptor Alpha Antibody (aa179-228)
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
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- Description
- Folate Receptor Alpha antibody LS-B5727 is an unconjugated rabbit polyclonal antibody to human Folate Receptor Alpha (FOLR1) (aa179-228). Validated for IHC and WB. Cited in 4 publications.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Adult folate-binding protein | FBP | Folate receptor alpha | FOLR1 | KB cells FBP | Folate binding protein | Folate receptor 1 | Folate receptor 1 (adult) | Folate receptor, adult | FOLR | FR-alpha
- Recommended Dilution: IHC-P
- 5 µg/ml
- Recommended Dilution: WB
- 0.2 - 1 µg/ml
- UniProt Number
- P15328
- NCBI GenBank
- NM_016730
- SwissProt
- P15328
Target
- Target
- FOLR1 / Folate Receptor Alpha
- Antigen Species
- Human
- Specificity
- Human FOLR1
- Epitope
- Human FOLR1
- Gene Name
- FOLR1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide located between aa179-228 of human FOLR1 (P15328, NP_000793). Percent identity by BLAST analysis: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% sodium azide, 2% sucrose
- Concentration
- 0.5 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy. Liang X, Luo M, Wei XW, Ma CC, Yang YH, Shao B, Liu YT, Liu T, Ren J, Liu L, He ZY, Wei YQ. Oncotarget. 2016;7:52207-52217.
PubMed: 27438147 · PMC: PMC5239545
Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma. Cai L, Michelakos T, Ferrone CR, Zhang L, Deshpande V, Shen Q, DeLeo A, Yamada T, Zhang G, Ferrone S, Wang X. Oncotarget. 2017;8:37646-37656.
PubMed: 28430580 · PMC: PMC5514937
Intraoperative near-infrared fluorescence imaging targeting folate receptors identifies lung cancer in a large-animal model. Keating JJ, Runge JJ, Singhal S, Nims S, Venegas O, Durham AC, Swain G, Nie S, Low PS, Holt DE. Cancer. 2017 May;123:1051-1060.
PubMed: 28263385 · PMC: PMC5341137
Folate Receptor Overexpression in Human and Canine Meningiomas-Immunohistochemistry and Case Report of Intraoperative Molecular Imaging. John T Pierce, Steve S Cho, Shayoni Nag, Ryan Zeh, Jun Jeon, David Holt, Amy Durham, MacLean P Nasrallah, Sunil Singhal, John Y K Lee. Neurosurgery. 2018 August.
PubMed: 30113687 · PMC: PMC6904722