LSBio
Follicular Dendritic Cells Antibody (clone Ki-M9R)

Follicular Dendritic Cells Antibody (clone Ki-M9R)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Rat
Format:Lyophilized
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$686.00each
Catalog Number: LS-C96398-500

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Overview

Description
Follicular Dendritic Cells antibody LS-C96398 is an unconjugated mouse monoclonal antibody to rat Follicular Dendritic Cells. Validated for IHC.
Application
IHC, IHC-P
Reactivity
Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: IHC-P
1:200

Target

Target
Follicular Dendritic Cells
Epitope
Ki-M9R detects a 49kDa cytoplasmic antigen. The epitope has not been further characterized. Antigen distribution: Isolated cells: Ki-M9R is negative with all peripheral blood cells and cells of the bone marrow or peritoneal cavity. Tissue sections: Ki-M9R specifically recognizes antigen trapping macrophages of the B-cell system such as sinus lining cells and dendritic reticulum cells. It is also positive on splenic metallophils. Macrophages in T-cell areas are negative with Ki- M9R. None of the macrophages in non-lymphoid organs are detected by Ki-M 9R. No cross-reactivity was found with other cell types at different tissue sites except with hepatic sinusoids. In vivo adminstration of Ki-M9R reveals a direct cytotoxicity to, and the elimation of Ki-M9R positive cells. Animals survive this treatment. Specificity: Rat: subpopulation of macrophages. Other species: not tested Comments: During the course of an infection the number of antigen trapping cells decreases while the number of antigen presenting cells increases. Antigen presenting Ki-M4R Ki-M9R Antigen trapping Course of an infection Unpublished data raised in The Institute of Pathology, Michaelisstrasse 11, 2300 Kiel, Germany

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
Ki-M9R

Immunogen

Immunogen
Peritoneal macrophages
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.