FK506 / Tacrolimus Antibody (clone FK1)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general) |
| Reactivity: | Other |
| Format: | Liquid |
$415.00each
Catalog Number: LS-C58196-0.2
Catalog Number: LS-C58196
For bulk orders or custom formulations:
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- Description
- Tacrolimus antibody LS-C58196 is an unconjugated mouse monoclonal antibody to synthetic Tacrolimus (FK506). Validated for ELISA.
- Application
- ELISA, IHC
- Reactivity
- Other
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
Target
- Target
- Synthetic FK506 / Tacrolimus
- Antigen Species
- Other
- Epitope
- Detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogeneic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- FK1
- Isotype
- IgM
Immunogen
- Immunogen
- FK-506-BSA conjugate.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- TBS, less than 0.1% Sodium Azide
- Preservative
- Yes
- Purification Method
- Other
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- TBS