LSBio
FGF21 Antibody (N-Terminus)

Anti-FGF21 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

FGF21 Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B5864-50

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Overview

Description
FGF21 antibody LS-B5864 is an unconjugated rabbit polyclonal antibody to human FGF21 (N-Terminus). Validated for IHC and WB. Cited in 3 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Fibroblast growth factor 21 | FGF-21 | FGF21
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.2 - 1 µg/ml
UniProt Number
Q9NSA1
SwissProt
Q9NSA1

Target

Target
FGF21
Antigen Species
Human
Specificity
Human FGF21
Epitope
Human FGF21
Gene Name
FGF21

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from N-Terminus of human FGF21 (Q9NSA1, NP_061986). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Horse, Pig, Guinea pig (100%); Rabbit (92%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Reversal of obesity-induced hypertriglyceridemia by (R)- alpha -lipoic acid in ZDF (fa/fa) rats. Yi X, Pashaj A, Xia M, Moreau R. Biochemical and biophysical research communications. 2013 Sep;439:390-5.

PubMed: 23994635


Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1a/PPARa-FGF21 signaling pathway in male Sprague Dawley rats undergoing catch-up growth. Gu C, Zeng Y, Tang Z, Wang C, He Y, Feng X, Zhou L. Molecular medicine reports. 2015;12:6451-60.

PubMed: 26323321 · PMC: PMC4626146


Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. Yamanishi K, Maeda S, Kuwahara-Otani S, Hashimoto T, Ikubo K, Mukai K, Nakasho K, Gamachi N, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Yamanishi H, Okamura H, Matsunaga H. Journal of translational medicine. 2018 November;16:314.

PubMed: 30453990 · PMC: PMC6245626

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