FFAR1 / GPR40 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$440.00each

Catalog Number: LS-C146689-1

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Description: GPR40 antibody LS-C146689 is an unconjugated rabbit polyclonal antibody to human GPR40 (FFAR1). Validated for IHC.
Application: IHC
Reactivity: Hu
Intended Use: RUO
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: FFAR | FFAR1 | FFA1R | G protein-coupled receptor 40 | GPCR40 | GPR40 | Free fatty acid receptor | Free fatty acid receptor 1 | G-protein coupled receptor 40
UniProt Number: O14842
NCBI GenBank: NM_005303, NP_005294.1
SwissProt: O14842

Target: Human FFAR1 / GPR40
Antigen Species: Hu
Epitope: GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.
Gene Name: FFAR1