FFAR1 / GPR40 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
$440.00each
Catalog Number: LS-C146689-1
Catalog Number: LS-C146689
For bulk orders or custom formulations:
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- Description
- GPR40 antibody LS-C146689 is an unconjugated rabbit polyclonal antibody to human GPR40 (FFAR1). Validated for IHC.
- Application
- IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- FFAR | FFAR1 | FFA1R | G protein-coupled receptor 40 | GPCR40 | GPR40 | Free fatty acid receptor | Free fatty acid receptor 1 | G-protein coupled receptor 40
- UniProt Number
- O14842
- NCBI GenBank
- NM_005303 | NP_005294.1
- SwissProt
- O14842
Target
- Target
- Human FFAR1 / GPR40
- Antigen Species
- Human
- Epitope
- GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.
- Gene Name
- FFAR1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Human GPR40 amino acids 210-222
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- TBS, pH 7.4, 0.5 mg/ml BSA, 0.02% Sodium Azide, 50% Glycerol
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- TBS