Western blot analysis of extracts of various cells.
EXO5 / Exonuclease 5 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$281.00each
Catalog Number: LS-C410042-20
Catalog Number: LS-C410042
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- Description
- Exonuclease 5 antibody LS-C410042 is an unconjugated rabbit polyclonal antibody to Exonuclease 5 (EXO5) from human. It is reactive with human and mouse. Validated for WB. Cited in 1 publication.
- Application
- IHC, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- C1orf176 | DEM1 | EXO5 | Exo V | Exonuclease 5
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- Q9H790
- NCBI GenBank
- NM_022774 | NP_073611.1
- SwissProt
- Q9H790
Target
- Target
- Human EXO5 / Exonuclease 5
- Antigen Species
- Human
- Epitope
- Human EXO5 / Exonuclease 5
- Gene Name
- EXO5
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-373 of human EXO5 (NP_073611.1). MAETREEETVSAEASGFSDLSDSEFLEFLDLEDAQESKALVNMPGPSSESLGKDDKPISLQNWKRGLDILSPMERFHLKYLYVTDLATQNWCELQTAYGKELPGFLAPEKAAVLDTGASIHLARELELHDLVTVPVTTKEDAWAIKFLNILLLIPTLQSEGHIREFPVFGEGEGVLLVGVIDELHYTAKGELELAELKTRRRPMLPLEAQKKKDCFQVSLYKYIFDAMVQGKVTPASLIHHTKLCLEKPLGPSVLRHAQQGGFSVKSLGDLMELVFLSLTLSDLPVIDILKIEYIHQETATVLGTEIVAFKEKEVRAKVQHYMAYWMGHREPQGVDVEEAWKCRTCTYADICEWRKGSGVLSSTLAPQVKKAK
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
- Concentration
- 0.626 mg/mL
- Volume
- 20 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Shashank Hambarde, Chi-Lin Tsai, Raj K Pandita, Albino Bacolla, Anirban Maitra, Vijay Charaka, Clayton R Hunt, Rakesh Kumar, Oliver Limbo, Remy Le Meur, Walter J Chazin, Susan E Tsutakawa, Paul Russell, Katharina Schlacher, Tej K Pandita, John A Tainer. Molecular cell. 2021 July;81:2989-3006.e9. PubMed: 34197737 PMC: PMC8720176