Positive WB detected in:A549 whole cell lysate,Hela whole cell lysate;All lanes:EPHA5 antibody at 3?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 115 KDa;Observed band size: 115 KDa;
EPHA5 / EPH Receptor A5 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C498804-50
Catalog Number: LS-C498804
For bulk orders or custom formulations:
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- Description
- EPH Receptor A5 antibody LS-C498804 is an unconjugated rabbit polyclonal antibody to human EPH Receptor A5 (EPHA5). Validated for ELISA, IF, IHC and WB.
- Application
- ELISA, IF, IHC, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- BSK | Brain-specific kinase | EHK-1 | EK7 | Eph homology kinase-1 | EPH receptor A5 | EPH-like kinase 7 | EPHA5 | EHK1 | HEK7 | Els1 | EPH homology kinase 1 | Rek7 | TYRO4 | CEK7 | Ephrin type-A receptor 5
- UniProt Number
- P54756
- NCBI GenBank
- NM_004439
- SwissProt
- P54756
Target
- Target
- Human EPHA5 / EPH Receptor A5
- Antigen Species
- Human
- Epitope
- Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
- Gene Name
- EPHA5
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Concentration
- 3.5 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS