Immunofluorescence imaging on fixed LL/2 cells.
EPHA2 / EPH Receptor A2 Antibody (Human Ephrin Type A receptor 2, clone 1C1)
Primary AntibodyLSBio Guarantee
| Antibody: | Human Recombinant Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence, Inhibitor / Activator Screening, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$551.00each
Catalog Number: LS-C777409-0.2
Catalog Number: LS-C777409
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- Description
- This EPHA2 / EPH Receptor A2 antibody is an unconjugated Human/Human chimeric recombinant monoclonal antibody. Validated for Agon, ELISA, Flo, IF, and WB.
- Application
- ELISA, FC, IF, Inh / Act Screen, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CTPA | EPH receptor A2 | Ephrin type-A receptor 2 | Epithelial cell kinase | ECK | EPHA2 | Sek-2 | ARCC2 | Soluble EPHA2 variant 1 | CTPP1
- UniProt Number
- P29317
- NCBI GenBank
- NM_004431 | NP_004422.2
- SwissProt
- P29317
Target
- Target
- Human EPHA2 / EPH Receptor A2
- Antigen Species
- Human
- Epitope
- 1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.
- Gene Name
- EPHA2
Antibody
- Host Species
- Human
- Clonality
- Recombinant Monoclonal
- Clone
- 1C1
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (aa 183-510). The Fab was subsequently converted to full length human IgG1.
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.02% ProClin™ 300.
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
- Recommended Storage Buffer
- PBS