Positive WB detected in:Mouse brain tissue;All lanes: EPHA1 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 109,53,52 kDa;Observed band size: 109,30 kDa;
EPHA1 / EPH Receptor A1 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C498803-50
Catalog Number: LS-C498803
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- Description
- EPH Receptor A1 antibody LS-C498803 is an unconjugated rabbit polyclonal antibody to EPH Receptor A1 (EPHA1) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
- Application
- ELISA, IF, IHC, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- EPH receptor A1 | Ephrin type-A receptor 1 | EPHT | ESK | EPH tyrosine kinase 1 | HEpha1 | Oncogene EPH | Soluble EPHA1 variant 1 | Soluble EPHA1 variant 2 | EPH tyrosine kinase | EPHA1 | EPHT1
- UniProt Number
- P21709
- NCBI GenBank
- NM_005232 | NP_005223.4
- SwissProt
- P21709
Target
- Target
- Human EPHA1 / EPH Receptor A1
- Antigen Species
- Human
- Epitope
- Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
- Gene Name
- EPHA1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant human Ephrin type-A receptor 1 protein (296-414AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Concentration
- 3 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS