EMA / MUC1 Antibody (clone VU-3D1, Concentrated)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$441.00each
Catalog Number: LS-C202432-100
Catalog Number: LS-C202432
For bulk orders or custom formulations:
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- Description
- MUC1 antibody LS-C202432 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for ELISA and IHC.
- Application
- ELISA, IHC, IHC-F, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | MUC1 | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
- UniProt Number
- P15941
- NCBI GenBank
- NM_002456 | NP_002447.4
- SwissProt
- P15941
Target
- Target
- Human EMA / MUC1
- Antigen Species
- Human
- Epitope
- VU-3D1 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of mAb VU3D1 is the 8-mer SAPDTRPA of the MUC1 tandem repeat as established with epitope fingerprinting.
- Gene Name
- MUC1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- VU-3D1
- Isotype
- IgG1
Immunogen
- Immunogen
- Live cells (107 cells/dose in PBS) of human breast cancer cell line ZR-75-1. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability of the hybridomas was established by subcloning four times.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.05% Sodium Azide
- Concentration
- 100 µg/mL
- Preservative
- Yes
- Purification Method
- Other
Storage & Handling
- Storage Conditions
- Store at 2-8°C.
- Recommended Storage Buffer
- PBS