LSBio
EIF5A Antibody (aa63-112)

Western blot of Human NCI-H226. EIF5A antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

EIF5A Antibody (aa63-112)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Western Blot
Reactivity:Human
Format:Liquid
See all Human EIF5A antibodies →
$433.00each
Catalog Number: LS-C186978-100

For bulk orders or custom formulations:

Request a Quote

Overview

Description
EIF5A antibody LS-C186978 is an unconjugated rabbit polyclonal antibody to human EIF5A (aa63-112). Validated for WB. Cited in 2 publications.
Application
IHC, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
EIF-4D | EIF-5A | EIF-5A-1 | EIF-5A1 | EIF5A | EIF5A1 | Initiation factor 5a | Rev-binding factor | EIF5AI
UniProt Number
P63241
SwissProt
P63241

Target

Target
Human EIF5A
Antigen Species
Human
Epitope
Human EIF5A
Gene Name
EIF5A

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic peptide located between aa63-112 of human EIF5A (P63241-2). Percent identity by BLAST analysis: Human, Chimpanzee, Mouse, Rat, Sheep, Bovine, Rabbit, Horse, Pig, Guinea pig, Chicken (100%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
100 Microliter
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction. YongTian Liang, Chengji Piao, Christine B Beuschel, David Toppe, Laxmikanth Kollipara, Boris Bogdanow, Marta Maglione, Janine Lützkendorf, Jason Chun Kit See, Sheng Huang, Tim O F Conrad, Ulrich Kintscher, Frank Madeo, Fan Liu, Albert Sickmann, Stephan J Sigrist. Cell reports. 2021 April;35:108941.

PubMed: 33852845


The inhibition of eIF5A hypusination by GC7, a preconditioning protocol to prevent brain death-induced renal injuries in a preclinical porcine kidney transplantation model. Sebastien Giraud, Thomas Kerforne, Jeremy Zely, Virginie Ameteau, Pierre Couturier, Michel Tauc, Thierry Hauet. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2020 December;20:3326-3340.

PubMed: 32400964

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.