The EGFR Isoform 3 Antibody is used in Western blot to detect EGFR Isoform 3 in HEK293 cell lysate.

EGFR Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity:	Human
Format:	Liquid

$402.00each

Catalog Number: LS-C413792-0.1

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Description: EGFR antibody LS-C413792 is an unconjugated rabbit polyclonal antibody to human EGFR. Validated for ELISA and WB.
Application: ELISA, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: EGFR | EGF Receptor | ERBB | ERBB1 | MENA | PIG61 | Proto-oncogene c-ErbB-1 | V-erb-b homolog | EGF-R | HER1
Recommended Dilution: ELISA: 1:500 - 1:1000
Recommended Dilution: WB: 1:200 - 1:500
UniProt Number: P00533
NCBI GenBank: NM_005228 | NP_005219.2
SwissProt: P00533

Target: Human EGFR
Antigen Species: Human
Epitope: Epidermal growth factor receptor (EGFR) is a receptor for EGF and for various members of the EGF family such as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. EGFR is involved in the control of cell growth and differentation. Binding of EGF to the receptor leads to dimerization, internalization of the EGF-receptor complex, induction of the tyrosine kinase activity, stimulation of cell DNA synthesis and cell proliferation. EGFR isoform 3 (sEGFR, p110) is a 77 kDa isoform consisting of the extracellular EGFR domain and a unique, truncated carboxy terminus region without transmembrane domain. EGFR isoform 3 is being investigated as a marker for epithelial ovarian cancer. This antibody is specific for isoform 3, it will not recognized full-length EGFR and EGFR vIII.
Gene Name: EGFR

Immunogen: KLH-conjugated synthetic peptide encomassing a sequence within the C-Terminus of human EGFR isoform 3.
Immunogen Type: Synthetic Peptide (Linear)