LSBio
EGFL7 Antibody (clone 2H2)

EGFL7 Antibody (clone 2H2)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity:Human
Format:Lyophilized
See all Human EGFL7 antibodies →
$449.00each
Catalog Number: LS-C153302-50

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Overview

Description
EGFL7 antibody LS-C153302 is an unconjugated mouse monoclonal antibody to human EGFL7. Validated for ELISA, IHC and WB. Cited in 2 publications.
Application
ELISA, IHC, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
EGF-like-domain, multiple 7 | EGFL7 | RP11-251M1.2 | VE-STATIN | NOTCH4-like protein | ZNEU1 | EGF-like protein 7 | MEGF7 | Vascular endothelial statin
UniProt Number
Q9UHF1
SwissProt
Q9UHF1

Target

Target
Human EGFL7
Antigen Species
Human
Epitope
Reacts with human 30 kD EGFL7 protein.
Gene Name
EGFL7

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
2H2
Isotype
IgG1
Light Chain
Kappa Light Chain

Immunogen

Immunogen
His-tagged EGFL-7 protein.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
100 mM Tris-glycine, 2% sucrose
Preservative
No
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at 4°C. For extended periods store in aliquots at -20°C.
Recommended Storage Buffer
100 mM Tris-glycine

EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia. Marius Bill, Aparna Pathmanathan, Malith Karunasiri, Changxian Shen, Matthew H Burke, Parvathi Ranganathan, Dimitrios Papaioannou, Nina C Zitzer, Katiri Snyder, Allison LaRocco, Allison E Walker, Zachary J Brannan, Ansel P Nalin, Aharon G Freud, Mikhail M Dikov, Xiaoli Zhang, Clara D Bloomfield, Ramiro Garzon, Adrienne M Dorrance. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 February;26:669-678.

PubMed: 31672772


Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia. Dimitrios Papaioannou, Changxian Shen, Deedra Nicolet, Betina McNeil, Marius Bill, Malith Karunasiri, Matthew H Burke, Hatice Gulcin Ozer, Selen A Yilmaz, Nina Zitzer, Gregory K Behbehani, Christopher C Oakes, Damian J Steiner, Guido Marcucci, Bayard L Powell, Jonathan E Kolitz, Thomas H Carter, Eunice S Wang, Krzysztof Mrózek, Carlo M Croce, Michael A Caligiuri, Clara D Bloomfield, Ramiro Garzon, Adrienne M Dorrance. Proceedings of the National Academy of Sciences of the United States of America. 2017 June;114:E4641-E4647.

PubMed: 28533390 · PMC: PMC5468639

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