LSBio
DSG1+2 / Desmoglein 1+2 Antibody (C-Terminus)

DSG1+2 / Desmoglein 1+2 Antibody (C-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Human, Mouse, Rat
Format:Lyophilized
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$986.00each
Catalog Number: LS-C22811-50

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Overview

Description
Desmoglein 1+2 antibody LS-C22811 is an unconjugated mouse monoclonal antibody to Desmoglein 1+2 (DSG1+2) (C-Terminus) from bovine. It is reactive with human, mouse, rat and other species. Validated for IF, IHC and WB.
Application
IF, IHC, IHC-F, IHC-P, WB
Reactivity
Bov, Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Bovine DSG1+2 / Desmoglein 1+2
Antigen Species
Bovine
Epitope
Species (tested so far) Human, bovine, rat, mouse. Recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells; does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide. Reactivities on Cultured Cell Lines (tested so far): A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines; bovine BMGE+H, BMGE-H, MDBK.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Isotype
IgG1

Immunogen

Immunogen
Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized
Preservative
No
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.