LSBio
DNAM-1 / CD226 Antibody (clone DX11, Low Endotoxin)

DNAM-1 / CD226 Antibody (clone DX11, Low Endotoxin)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunoprecipitation
Reactivity:Human
Format:Liquid
See all Human DNAM-1 / CD226 antibodies →
$654.00each
Catalog Number: LS-C44510-0.5

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Overview

Description
CD226 antibody LS-C44510 is an unconjugated mouse monoclonal antibody to human CD226 (DNAM-1). Validated for Flow and IP.
Application
FC, IHC, IP
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Adhesion glycoprotein | CD226 molecule | CD226 | CD226 antigen | DNAM-1 | DNAM1 | DNAX accessory molecule-1 | TLiSA1 | PTA1 | DNAX accessory molecule 1
Recommended Dilution: FC
1:50 - 1:200
UniProt Number
Q15762
SwissProt
Q15762

Target

Target
Human DNAM-1 / CD226
Antigen Species
Human
Epitope
Recognizes human CD226, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
Gene Name
CD226

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
DX11
Isotype
IgG1

Immunogen

Immunogen
Human cytotoxic T lymphocyte clone
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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