Positive WB detected in:Mouse skeletal muscle tissue;All lanes: DNAJB6 antibody at 2.8ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 37,27,36,31 kDa;Observed band size: 37 kDa;

DNAJB6 Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot
Reactivity:	Human, Mouse
Format:	Liquid

$300.00each

Catalog Number: LS-C500061-50

Unit Size

Quantity

For bulk orders or custom formulations:

Overview

Description: DNAJB6 antibody LS-C500061 is an unconjugated rabbit polyclonal antibody to DNAJB6 from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
Application: ELISA, IF, WB
Reactivity: Hu, Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: DNAJB6 | DnaJ-like 2 protein | HSJ2 | LGMD1E | MRJ | MSJ-1 | MSJ1 | DJ4 | DnaJ | Heat shock protein J2 | HHDJ1 | HSJ-2
UniProt Number: O75190
NCBI GenBank: NM_005494 | NP_005485.1
SwissProt: O75190

Target

Target: Human DNAJB6
Antigen Species: Human
Epitope: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Gene Name: DNAJB6