IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-DICER1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
DICER1 / Dicer Antibody (aa1666-1922, clone OTI1G8)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$443.00each
Catalog Number: LS-C338518-100
Catalog Number: LS-C338518
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- Description
- Dicer antibody LS-C338518 is an unconjugated mouse monoclonal antibody to human Dicer (DICER1) (aa1666-1922). Validated for IHC. Cited in 1 publication.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- DCR1 | Dicer | Dicer 1, ribonuclease type III | DICER1 | Endoribonuclease Dicer | HERNA | Helicase-moi | MNG1 | Helicase with RNase motif | Dicer1, Dcr-1 homolog | Helicase MOI | K12H4.8-LIKE | KIAA0928
- Recommended Dilution: IHC-P
- 1:150
- UniProt Number
- Q9UPY3
- NCBI GenBank
- NM_030621 | NP_085124.2
- SwissProt
- Q9UPY3
Target
- Target
- Human DICER1 / Dicer
- Antigen Species
- Human
- Epitope
- Human DICER1 / Dicer
- Gene Name
- DICER1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- OTI1G8
- Isotype
- IgG2b
Immunogen
- Immunogen
- Human recombinant protein fragment corresponding to amino acids 1666-1922 of human DICER1 (NP_085124) produced in E. coli.
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
- Concentration
- 1 mg/mL
- Volume
- 100 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas. Raisa A Reyes-Castro, Shin-Yu Chen, Jacob Seemann, Samrat T Kundu, Don L Gibbons, Swathi Arur. Science advances. 2023 July;9:eadf6210. PubMed: 37494452 PMC: PMC10577638