Positive WB detected in:Mouse liver tissue,Mouse kidney tissue;All lanes:DEF6 antibody at 4ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 74 kDa;Observed band size: 74 kDa;

DEF6 Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:	Human, Mouse
Format:	Liquid

$300.00each

Catalog Number: LS-C502008-50

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Overview

Description: DEF6 antibody LS-C502008 is an unconjugated rabbit polyclonal antibody to DEF6 from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
Application: ELISA, IF, IHC, WB
Reactivity: Hu, Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: DEF6 | DEF-6 | IBP | SLAT | SWAP70L | IRF4-binding protein
UniProt Number: Q9H4E7
NCBI GenBank: NM_022047 | NP_071330.3
SwissProt: Q9H4E7

Target

Target: Human DEF6
Antigen Species: Human
Epitope: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
Gene Name: DEF6