Immunohistochemical staining of endogenous human RIG-I in different human tissues (paraffin sections) using anti-RIG-I, mAb (Alme-1) . .Different human normal tissues (A: Nasopharynx; B: Colon; C: Endometrium) or cancer tissues (D: Breast; E: Skin; F: Ovarian) were stained with anti-RIG-I, mAb (Alme-1) by standard immunohistochemistry. This image was taken for the unconjugated form of this product. Other forms have not been tested.
DDX58 / RIG-1 / RIG-I Antibody (aa201-713, clone Alme-1)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$516.00each
Catalog Number: LS-C344928-100
Catalog Number: LS-C344928
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- Description
- RIG-I antibody LS-C344928 is an unconjugated mouse monoclonal antibody to RIG-I (DDX58 / RIG-1) (aa201-713) from human. It is reactive with human and mouse. Validated for IHC, IP and WB. Cited in 1 publication.
- Application
- IHC, IHC-P, IP, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- DDX58 | RIG-1 | RIG-I | RLR-1 | Retinoic acid inducible gene I | RIG-I-like receptor 1 | RIGI | DEAD box protein 58 | RNA helicase RIG-I
- Recommended Dilution: IP
- 1:200
- Recommended Dilution: WB
- 1:1000
- UniProt Number
- O95786
- NCBI GenBank
- NM_014314 | NP_055129.2
- SwissProt
- O95786
Target
- Target
- Human DDX58 / RIG-1 / RIG-I
- Antigen Species
- Human
- Epitope
- Recognizes human and mouse RIG-I.
- Gene Name
- DDX58
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- Alme-1
- Isotype
- IgG1
Immunogen
- Immunogen
- Recombinant human RIG-I (aa 201-713).
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.02% Sodium Azide, 10% Glycerol
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Mechanism of Nucleic Acid Sensing in Retinal Pigment Epithelium (RPE): RIG-I Mediates Type I Interferon Response in Human RPE. Joshua Schustak, Michael Twarog, Xiaoqiu Wu, Henry Y Wu, Qian Huang, Yi Bao. Journal of immunology research. 2021 Jun;2021:9975628. PubMed: 34239945 PMC: PMC8235977