Immunohistochemistry of paraffin-embedded human liver cancer using CYR61 Antibody at dilution of 1:100

CYR61 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C500205-50

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Description: CYR61 antibody LS-C500205 is an unconjugated rabbit polyclonal antibody to human CYR61. Validated for ELISA and IHC.
Application: ELISA, IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: GIG1 | IGFBP10 | Protein CYR61 | CCN family member 1 | CCN1 | CYR61 | IBP-10 | IGF-binding protein 10 | IGFBP-10 | Protein GIG1
UniProt Number: O00622
NCBI GenBank: NM_001554 | NP_001545.2
SwissProt: O00622

Target: Human CYR61
Antigen Species: Human
Epitope: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Gene Name: CCN1