LSBio
Complement C8 Antibody (clone 056B-373)

Complement C8 Antibody (clone 056B-373)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Western Blot
Reactivity:Human
Format:Liquid
See all Human Complement C8 antibodies →
$573.00each
Catalog Number: LS-C44994-0.1

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Overview

Description
Complement C8 antibody LS-C44994 is an unconjugated mouse monoclonal antibody to human Complement C8. Validated for ELISA, Flow, IHC and WB.
Application
ELISA, FC, IHC, IHC-F, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Human Complement C8
Antigen Species
Human
Epitope
Recognizes complement component 8 (C8), a 151 kD member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
056B-373
Isotype
IgG1

Immunogen

Immunogen
Purified human C8.
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
BBS, 0.1% Sodium Azide
Concentration
1.08 mg/mL
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
bbs

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