LSBio
CIDEA / CIDE-A Antibody (Biotin)

CIDEA / CIDE-A Antibody (Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Human
Format:Liquid
See all Human CIDEA / CIDE-A Antibodies →
$300.00each
Catalog Number: LS-C498627-50

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Overview

Description
CIDE-A antibody LS-C498627 is a biotin-conjugated rabbit polyclonal antibody to human CIDE-A (CIDEA). Validated for ELISA.
Application
ELISA
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CIDE-A | CIDEA | Cell death activator CIDE-A
UniProt Number
O60543
NCBI GenBank
NM_001279, NP_001270.1
SwissProt
O60543

Target

Target
Human CIDEA / CIDE-A
Antigen Species
Hu
Epitope
Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.
Gene Name
CIDEA

Antibody

Host Species
Rb
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human Cell death activator CIDE-A protein (1-51AA)
Immunogen Type
Cell

Format

Conjugate/Label
Biotin
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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